Methods of detecting compounds which bind to the P.sub.2U receptor

US5607836A · kind A · utility

Assignee

• The Curators of the University of Missouri · US

Inventors

• Richard C. Boucher, Jr. · Chapel Hill, US
• Gary A. Weisman · Columbia, US
• John T. Turner · Ashland, US
• Thomas K. Harden · Westfield, US
• Claude E. Parr · Chapel Hill, US
• Daniel M. Sullivan · Lutz, US
• Laura J. Erb · Columbia, US
• Kevin D. Lustig · Cambridge, US

Key dates

• Filing date: May 19, 1995
• Grant date: Mar 4, 1997
• Expiry date: May 19, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Isolated DNAs encoding the human P.sub.2U receptor are disclosed, along with vectors and host cells containing the same and methods of using the same. Host cells which are essentially free of endogenous P.sub.2U receptor expression, and which express a heterologous P.sub.2U receptor such as a murine P.sub.2U receptor, are also disclosed, along with methods of using the same.