Substituted 4-phenylthiazole derivatives, process for their preparation and pharmaceutical compositions containing them
US5607952A · kind A · utility
12Cited by
1References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 22, 1995 |
| Grant date | Mar 4, 1997 |
| Priority date | — |
| Expiry date | Dec 22, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns compounds of formula ##STR1## in which R, A, R.sub.1 and Y are as defined in claim 1. The instant compounds have an affinity for the fibrinogen receptor: the complex of the glycoproteins IIb/llIa (GP IIb/IIIa); more particularly, the subject of the present invention is new inhibitors of platelet aggregation which are antagonists of the GP IIb/IIIa receptors, of nonpeptide structure, which are active via the parenteral and oral routes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.