Virus-safe blood coagulation factor XIII preparation
US5610147A · kind A · utility
13Cited by
3References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jul 26, 1994 |
| Grant date | Mar 11, 1997 |
| Priority date | — |
| Expiry date | Jul 26, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/83
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a virus-safe blood coagulation factor XIII preparation, which is obtained by heating an aqueous solution containing the blood coagulation factor XIII having a specific activity of at least 2 U/mg of total protein, wherein the solution containing less than 10% of known stabilizers selected from the group consisting of sugars, polyols, amino acids, peptides and carboxylic acids, as well as less than 0.5 mol ammonium sulfate per liter, wherein the heating is effected for a period of time sufficient to inactivate infectious agents, preferably for a period of time of from 30 min to 100 h.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.