Topical 5-fluorouracil prodrug composition and method
US5610160A · kind A · utility
1Cited by
3References
10Claims
0Family size
Inventors
Key dates
| Filing date | Nov 22, 1994 |
| Grant date | Mar 11, 1997 |
| Priority date | — |
| Expiry date | Nov 22, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/505
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition in unit dosage form adapted for topical administration to a human or non-human animal in need thereof comprising a pharmacologically effective amount of a prodrug of 5-fluorouracil having the formula: ##STR1## wherein R.sub.3 is bonded to C=O by a carbon-to-carbon bond and is a group such that the prodrug (1) has an enhanced delivery across topical membranes and (2) hydrolyzes after delivery to 5-fluorouracil.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.