Sulfonamidocarbonylpyridine-2-carboxamides and pyridine-n-oxides which are useful as pharmaceuticals

US5610172A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Klaus Weidmann · Kronberg, DE
• Martin Bickel · Frankfurt am Main, DE
• Volkmar G unzler-Pukall · Marburg, DE

Key dates

• Filing date: Mar 24, 1995
• Grant date: Mar 11, 1997
• Expiry date: Mar 24, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation, and their use as pharmaceuticals The invention relates to sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-N-oxides according to the formula I ##STR1## Said compounds are used as pharmaceuticals against fibrotic disorders, as fibrosuppressants and as inhibitors of proline hydroxylase and of collagen biosynthesis.