Tachykinin (NK1) receptor antagonists
US5610176A · kind A · utility
18Cited by
1References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 7, 1995 |
| Grant date | Mar 11, 1997 |
| Priority date | — |
| Expiry date | Sep 7, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns tachykinin antagonists. The compounds are alcohols, amines and prodrugs of nonpeptides which have utility in treating disorders mediated by tachykinins. Such disorders are respiratory, inflammatory, gastrointestinal, ophthalmic, allergies, pain, vascular, diseases of the central nervous system, and migraine. Methods of preparing compounds and novel intermediates are also included. The compounds are expected to be especially useful in asthma, multiple sclerosis, rheumatoid arthritis, the management of pain, migraine, and antiemetic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.