Reagent useful for cleaving and process for using this reagent
US5610275A · kind A · utility
0Cited by
0References
9Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 31, 1994 |
| Grant date | Mar 11, 1997 |
| Priority date | — |
| Expiry date | Oct 31, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/061
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a reagent which is useful for cleaving an alkoxycarbonyl group from a functional group which it is protecting and to a process for using this reagent. This reagent comprises a phenol, a diluent, and a hydrohalic or hydropseudohalic acid, the acidity of which is at least equal to that of formic acid. The method is advantageously applied in the synthesis of peptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.