Process for preparing dioxolenone derivatives used for making prodrug esters and intermediates
US5610314A · kind A · utility
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11Claims
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Key dates
| Filing date | Apr 3, 1995 |
| Grant date | Mar 11, 1997 |
| Priority date | — |
| Expiry date | Apr 3, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D317/40
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is provided for preparing dioxolenone derivatives of the structure ##STR1## wherein R is alkyl or aryl and R.sub.3 is CO.sub.2 R.sub.2 (where R.sub.2 is alkyl or arylalkyl such as benzyl, diphenylmethyl or para-methoxybenzyl). Intermediates produced in the above process are also provided as well as a method for preparing squalene synthetase inhibitors employing such intermediates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.