Streptomyces sp. MA 7074 (ATCC 55605) used for microbial synthesis of HIV protease inhibitors
US5612217A · kind A · utility
2Cited by
5References
1Claims
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Key dates
| Filing date | Oct 25, 1994 |
| Grant date | Mar 18, 1997 |
| Priority date | — |
| Expiry date | Oct 25, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/886
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Biotransformation products of a fermentation with culture MA7074 are potent HIV protease inhibitors. These products are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.