Methods for the genetic modification of endogenous genes in animal cells by homologous recombination
US5614396A · kind A · utility
171Cited by
2References
32Claims
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Key dates
| Filing date | Feb 22, 1994 |
| Grant date | Mar 25, 1997 |
| Priority date | — |
| Expiry date | Feb 22, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2217/05
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for producing animal cells, chimeric or transgenic non-human animals which contain a desired gene sequence inserted into a predetermined gene sequence. The method permits the production of animal cells and non-human animals which have subtle and precise modifications of gene sequence and expression relative to natural non-human animals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.