Method of determining the virus inactivation capacity of an inactivation treatment

US5614405A · kind A · utility

Assignee

• Immuno Aktiengesellschaft · AT

Inventors

• Johann Eibl · Wien, AT
• Friedrich Elsinger · Wien, AT
• Yendra Linnau · Wien, AT
• Gunther Wober · Oberwaltersdorf, AT

Key dates

• Filing date: Jun 10, 1994
• Grant date: Mar 25, 1997
• Expiry date: Jun 10, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61L2/0023
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention is directed to a method of evaluating viral reduction capability of a viral inactivation step in a viral inactivation procedure. The method requires spiking a biological product with a virus more than once during the viral inactivation step so that a virus reduction factor can be calculated.