12-aminopyridazinopyrroloisoquinoline compounds

US5614516A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Walter L osel · Gau-Algesheim, DE
• Otto Roos · Bad Kreuznach, DE
• Gerd Schorrenberg · Gau-Algesheim, DE
• Helmut Ensinger · Wackernheim, DE
• Richard Reichl · Ingelheim am Rhein, DE

Key dates

• Filing date: Feb 7, 1995
• Grant date: Mar 25, 1997
• Expiry date: Feb 7, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/28
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to new 12-amino-pyridazino-[4',5':3,4]-pyrrolo[2,1-a]isoquinolines of general formula (I) ##STR1## wherein --NR.sub.1 R.sub.2 represents an amino or substituted amino group, and acid addition salts thereof. The new active substances have potential use in pharmaceutical compositions for treating cardiac insufficiency and cerebral metabolic disorders.