2,4-and 2,5-bistetrazolylpyridines, a process for the preparation thereof and the use thereof as pharmaceuticals

US5614537A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Gerrit Schubert · Kelkheim, DE
• Ekkehard Baader · Königstein, DE
• Martin Bickel · Frankfurt am Main, DE
• Volkmar G unzler-Pukall · Marburg, DE

Key dates

• Filing date: Jun 5, 1995
• Grant date: Mar 25, 1997
• Expiry date: Jun 5, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates 2,4- and 2,5-bistetrazolylpyridines. Said compounds inhibit the enzymes proline hydroxylase and lysine hydroxylase and bring about a selective inhibition of collagen biosynthesis. They are used as fibrosuppressants and immunosuppressants.