Method for the diagnosis of CADASIL
US5616462A · kind A · utility
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6Claims
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Key dates
| Filing date | Feb 28, 1994 |
| Grant date | Apr 1, 1997 |
| Priority date | — |
| Expiry date | Feb 28, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/172
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Genotypic diagnosis of CADASIL for symptomatic or at risk individuals or fetuses belonging to a family suspected of being affected by CADASIL is carried out by detecting DNA polymorphisms genetically linked to the mutated gene responsible for CADASIL, these DNA polymorphisms being located in the genetic interval of the chromosome 19 flanked by the microsatellites D198221 and D19S215 and including these microsatellites.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.