Oligopeptide antiretroviral agents
US5616606A · kind A · utility
20Cited by
1References
31Claims
0Family size
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Key dates
| Filing date | Aug 2, 1995 |
| Grant date | Apr 1, 1997 |
| Priority date | — |
| Expiry date | Aug 2, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D207/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Oligopeptide antiretroviral agents are represented by formula (I), wherein A is a moiety bearing a positive charge and of a size which avoids steric inhibition of binding of said compound to nucleic acid sequences associated with the cellular activity of retroviruses; R.sub.1 is a moiety derived from a dicarboxylic acid; Hew is a five-membered heterocyclic moiety; y and z are independently 0, 1, 2 or 3; and x is 0 or 1. These compounds exhibit antiretroviral activity, especially against Human Immunodeficiency Virus (HIV). ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.