Process for preparing homocystein analogs useful as intermediates for compounds containing a fused bicyclic ring
US5616775A · kind A · utility
6Cited by
30References
3Claims
0Family size
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Key dates
| Filing date | Feb 5, 1996 |
| Grant date | Apr 1, 1997 |
| Priority date | — |
| Expiry date | Feb 5, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Homocysteine analogs of the formula ##STR1## wherein P.sub.1 is a nitrogen protecting group and R.sub.6 is alkyl, substituted alkyl or benzyl are prepared by esterifying N-protected L-methionine, oxidizing, treating the resulting sulfoxide with an acid anhydride, treating the resulting product with an alkali metal hydroxide followed by removal of formaldehyde and the treatment with an acid anhydride or acid halide. The L-homocysteine analogs are useful as intermediates in the preparation of compounds containing a fused bicyclic ring.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.