Vaccine against Neisseria meningitidis infections
US5618541A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 2, 1993 |
| Grant date | Apr 8, 1997 |
| Priority date | — |
| Expiry date | Jun 2, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/871
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A vaccinal pharmaceutical composition which comprises, as therapeutic agents, at least a first and a second molecule capable of binding to human transferrin; the said first molecule originating from a first strain of N. meningitidis which possesses a human transferrin receptor in which the lower molecular weight subunit (Tbp2) is recognised by an antiserum to the receptor of N. meningitidis strain 2394 (receptor 2394) and is not recognised by an antiserum to the receptor of N. meningitidis strain 2169 (receptor 2169); and at least a second molecule originating from a second strain of N. meningitidis which possesses a human transferrin receptor in which the lower molecular weight subunit (Tbp2) is recognised by an anti-receptor 2169 antiserum and is not recognised by an anti-receptor 2394 antiserum.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.