Patent · US Expired

Dibekacin derivatives and arbekacin derivatives active against resistant bacteria, and the production thereof

US5618795A · kind A · utility

8Cited by
4References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 8, 1995
Grant dateApr 8, 1997
Priority date
Expiry dateSep 8, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H15/234
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

As new dibekacin derivatives and new arbekacin derivatives are now provided 2"-amino-2"-deoxydibekacin, 2"-amino-5,2"-dideoxydibekacin, 2"-amino-2"-deoxyarbekacin, 2"-amino-5,2"-dideoxyarbekacin, 2"-amino-5,2"-dideoxy-5-epi-fluoroarbekacin and 2"-amino-5,2"-dideoxy-5-epi-aminoarbekacin which all exhibit high antibacterial activity against a wide variety of gram-positive and gram-negative bacteria, including resistant bacteria such as methicillin-resistant Staphylococcus aureus and which are of low toxicity to mammals and are useful as antibacterial agent for treatment of bacterial infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.