Thermally-gelling drug delivery vehicles containing cellulose ethers
US5618800A · kind A · utility
11Cited by
24References
39Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 23, 1995 |
| Grant date | Apr 8, 1997 |
| Priority date | — |
| Expiry date | Aug 23, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Drug delivery vehicles which reversibly increase in either loss modulus or storage modulus, or both, upon contact with the eye, skin, mucous membrane or body cavity are disclosed. The vehicles contain one or more nonionic substituted cellulose ethers and do not require a charged surfactant or a pH-sensitive polymer for such increase in loss modulus or storage modulus, or both, upon administration. In one embodiment, the vehicles gel upon instillation in the eye.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.