Patent · US Expired

Method for the synthesis of anthrapyrazolones

US5618944A · kind A · utility

0Cited by
3References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 10, 1995
Grant dateApr 8, 1997
Priority date
Expiry dateJan 10, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D231/54
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to compounds, including 5-chloro-2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-7-[2,4,6-trimethylphen yl)methoxy]anthra[1,9-cd]pyrazol-6(2H)-one and analogs thereof, which are useful as intermediates for the synthesis of anthrapyrazolone anticancer agents, including losoxantrone. This invention also relates to methods for the synthesis of anthrapyrazolone anticancer agents, including losoxantrone.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.