Process for the sulfinylation of heterocyclic compounds
US5618945A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 22, 1995 |
| Grant date | Apr 8, 1997 |
| Priority date | — |
| Expiry date | Feb 22, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D231/44
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a novel process for the sulfinylation of heterocyclic compounds, which comprises reacting: PA1 a compound of the formula RS(O)X, in which R is a linear or branched alkyl group having from 1 to 4 carbon atoms, which is substituted with one or more identical or different halogen atoms and X is a halogen atom, the hydroxyl group or one of the salts thereof, a group --NR.sub.2 R.sub.3, R.sub.2 and R.sub.3 being alkyl or haloalkyl groups of 1 to 4 carbon atoms, or an aryloxy or aralkoxy group, in which the aryl part preferably corresponds to a phenyl group, which is optionally substituted with one or more halogen atoms or alkyl or haloalkyl groups of 1 to 4 carbon atoms, PA1 with a heterocyclic compound Het chosen from the group consisting of pyrroles, pyrazoles, imidazoles, oxazoles, isoxazoles, thiazoles, isothiazoles and triazoles, all of these heterocycles Het optionally being substituted with one or more atoms or groups chosen from halogen, amine, alkylamine, dialkylamine, nitrile, aryl, and aryl substituted with one or more halogen atoms and/or one or more alkyl, haloalkyl or SF.sub.5 groups.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.