Compositions for treating and inhibiting gastric and duodenal ulcers
US5620964A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 5, 1995 |
| Grant date | Apr 15, 1997 |
| Priority date | — |
| Expiry date | Jun 5, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition for treating and/or inhibiting gastric and duodenal ulcers, comprising an oligosaccharide selected from the group consisting of Formula I ##STR1## or a mixture thereof; wherein: PA1 X is independently OH or NHAc; PA1 Y is independently H, or an amino acid or a peptide of 2-100, preferably 2-20, amino acids; and PA1 W, W', and W" are each independently H or ##STR2## where Z is independently H or a pharmaceutically acceptable cation; and P is independently H or ##STR3## where Z is defined as above; wherein at least one of W, W' or W" is an .alpha.-N-acetylneuraminic acid moiety, and PA2 wherein W' and W" are not simultaneously .alpha.-N-acetylneuraminic acid moiety PA2 with the proviso that the compound of Formula II is not NAN .alpha.(2.fwdarw.3)Gal .beta.1-4 Glu or NAN .alpha.(2.fwdarw.6)Gal .beta.1-4 Glu; and a kit for detecting the presence of Helicobacter pylori comprising at least one compound of the Formula I or II, are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.