Antimitotic binary alkaloid derivatives from catharanthus roseus
US5620985A · kind A · utility
21Cited by
6References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 19, 1996 |
| Grant date | Apr 15, 1997 |
| Priority date | — |
| Expiry date | Jan 19, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel fluorinated derivatives of the vinblastine and vinorelbine family of general formula (1), ##STR1## wherein the symbols have the meanings indicated in the Specification and Claims, and the therapeutically-acceptable salts of these molecules, as well as pharmaceutical compositions thereof. The invention also concerns the application of said compounds in the treatment of a cancer pathology and their methods of preparation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.