17 urea, thiourea, thiocarbamyl and carbamyl4-azasteroid 5-reductase inhibitors useful in the prevention and treatment of hyperandrogenic disorders
US5620986A · kind A · utility
10Cited by
18References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 1, 1995 |
| Grant date | Apr 15, 1997 |
| Priority date | — |
| Expiry date | Mar 1, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J73/005
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel substituted 4-azasteroid 5-.alpha.-reductase inhibitors of formula (I), wherein A is (a), (b) or (c), are claimed as well as pharmaceutically acceptable salts and formulations thereof. These compounds are effective inhibitors of testosterone 5.alpha.-reductase(s) and are thus useful in the treatment of a number of hyperandrogenic conditions including benign prostatic hypertrophy, acne, seborrhea, female hirsutism, and male and female pattern baldness (alopecia).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.