Process for making morphine-6-glucuronide or substituted morphine-6-glucuronide
US5621087A · kind A · utility
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17Claims
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Key dates
| Filing date | Feb 4, 1994 |
| Grant date | Apr 15, 1997 |
| Priority date | — |
| Expiry date | Feb 4, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H17/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
##STR1## Morphine-6-glucuronide or substituted morphine-6-glucuronide of formulae (I) is made by conjugation of a glucuronate ester and/or substituted glucuronate ester with morphine or substituted morphine in the presence of a Lewis acid catalyst and in the absence of silver catalysts and barium hydroxide and other heavy metal derivatives.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.