Patent · US Expired

Piperazine derivatives as 5-HT antagonists

US5622951A · kind A · utility

2Cited by
5References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 24, 1995
Grant dateApr 22, 1997
Priority date
Expiry dateMay 24, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Piperazine derivatives of formula (I) and their pharmaceutically acceptable salts are 5-HT.sub.1A binding agents and may be used, for example, as anxiolytics. In the formula, R and R.sup.3 are hydrogen or lower alkyl or R.sup.3 is spirocycloalkyl, R.sup.1 and R.sup.2 are aryl or heteroaryl radicals and n is 1 or 2 and m is 1 to 3 and the total of n+m is 2-4. ##STR1##

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.