Spin trapping pharmaceutical compositions and methods for use thereof
US5622994A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Mar 15, 1994 |
| Grant date | Apr 22, 1997 |
| Priority date | — |
| Expiry date | Mar 15, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/40
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Spin trapping compositions in general have now been discovered to be effective in treating a variety of disorders, including disorders such as those arising from ischemia, infection, inflammation, exposure to radiation or cytotoxic compounds, not just of the central and peripheral nervous systems but of peripheral organ disease having a wide variety of etiologies. In the preferred embodiment, the compositions for treating tissue damage from ischemia contain PBN, or active derivatives thereof, in a suitable pharmaceutical carrier for intravenous, oral, topical, or nasal/pulmonary administration. Many different disorders can be treated using these compounds, including diseases or disorders of the central and peripheral nervous systems, and disorders arising from ischemia, infection, inflammation, oxidation from exposure to radiation or cytotoxic compounds, as well as due to naturally occurring processes such as aging.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.