Silicone modified phospholipid compositions
US5623043A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 12, 1995 |
| Grant date | Apr 22, 1997 |
| Priority date | — |
| Expiry date | Apr 12, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q5/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A silicone-containing phospholipid composition is provided having the general formula: ##STR1## wherein: A can be H, M or R--Y--; A, can be H, OH, OM or R--Y--O; A.sub.1 is selected from H, OH, OM or R--Y--O--; M is a cation; Y is alkylene or substantially alkylene; x is 0 or an integer from 1-5; and R is a quaternized organosilicone amidoamine reactant moiety of the formula: ##STR2## wherein: R.sub.10 is the silicone backbone chain to which at least one pyrrolidone containing amidoamine functional group is attached; R.sub.6 is hydrogen, alkyl, hydroxyalkyl, alkenyl cycloalkyl or polyoxyalkylene; R.sub.7 and R.sub.8 are selected from alkyl, hydroxyalkyl, carboxyalkyl and polyoxyalkylene; F is linear or branched alkylene; X.sup.- is an anion; n is 0 or 2; n.sup.1 is 0 or 1; n.sup.2 is 0 or 1; n.sup.3 is an integer from 2 to 12. B is --NR.sub.11 sulfur or oxygen, wherein R11 is hydrogen or lower alkyl; with the proviso that when n.sup.1 is 0 and n.sup.2 is 1, n.sup.1 is 1, when n is 2 and n.sup.2 is 1, n.sup.1 is 0 or 1 and when n is 2 and n.sup.2 is 0, n.sup.1 is 0; and; d is one or greater.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.