Method of treating HIV infection and related secondary infections with defibrotide
US5624912A · kind A · utility
8Cited by
3References
17Claims
0Family size
Inventors
Key dates
| Filing date | Jan 24, 1994 |
| Grant date | Apr 29, 1997 |
| Priority date | — |
| Expiry date | Jan 24, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Oligonucleotides, polynucleotides and derivatives thereof, such as defibrotide, are agents of genetic modulation at the levels of transcription, translation, secondary messengers and cellular signal transduction systems. Such agents can be used to treat HIV infection. Preferably, treatment involves modifying the dose of such agents in response to observed fluctuations (e.g., increase, decrease, appearance, disappearance) in normal, disease and repair markers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.