Carbocyclic nucleoside analogs useful as immunosuppressants
US5624930A · kind A · utility
0Cited by
8References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 22, 1995 |
| Grant date | Apr 29, 1997 |
| Priority date | — |
| Expiry date | Mar 22, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to a method of effecting immunosuppression in a patient in need thereof comprising administering an effective amount of a compound of the formula (1) ##STR1## wherein the hydroxy substituent on the cyclopentenyl ring is in the CIS configuration relative to the bicyclic substituent, PA0 Y.sub.3, Y.sub.7, Y.sub.8 and Y.sub.9 are each independently nitrogen or a CH group, PA0 Q is NH.sub.2, halogen or hydrogen, and PA0 Z is hydrogen, halogen, or NH.sub.2 ; or a pharmaceutically-acceptable salt thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.