Naphthyloxyacetic acid
US5624959A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 8, 1994 |
| Grant date | Apr 29, 1997 |
| Priority date | — |
| Expiry date | Dec 8, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C311/29
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
(1) Naphthyloxyaetic acid represented by the compound of the formula (I): ##STR1## and non-toxic salts thereof, (2) process for the preparation of the compounds represented by the compound of the formula (I) described hereinbefore, (3) PGE.sub.2 antagonist or agonist containing the compound represented by the compound of the formula (I) as the active ingredient. The compounds represented by the compounds of the formula (I) can be adapted to medicines which possess an inhibitory effect of uterine contraction, an analgesic action, an inhibitory effect of digestive peristalsis, a sleep-inducing effect as PGE.sub.2 antagonists, and an uterine contractile activity, a promoting effect of digestive peristalsis, a suppressive effect of gastric acid secretion, hypotensive activity as PGE.sub.2 agonists. The compounds bind to PGE.sub.2 receptor and have an activity of antagonist or agonist against the action thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.