Preparation of prothrombin time reagents from recombinant human tissue factor and purified natural and synthetic phospholipids
US5625036A · kind A · utility
23Cited by
4References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 10, 1995 |
| Grant date | Apr 29, 1997 |
| Priority date | — |
| Expiry date | Jan 10, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2405/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A prothrombin time reagent is disclosed for use in a prothrombin time test. The reagent utilizes recombinant human tissue factor, phospholipids of a natural or synthetic origin, a buffer composition and calcium ion. Stabilizers and salts may also be utilized in the reagent. In addition, a method for creating lipid micelles containing tissue factor is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.