Modified green fluorescent proteins
US5625048A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 10, 1994 |
| Grant date | Apr 29, 1997 |
| Priority date | — |
| Expiry date | Nov 10, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/855
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Modifications in the sequence of Aequorea wild-type GFP provide products having markedly different excitation and emission spectra from corresponding products from wild-type GFP. In one class of modifications, the product derived from the modified GFP exhibits an alteration in the ratio of two main excitation peaks observed with the product derived from wild-type GFP. In another class, the product derived from the modified GFP fluoresces at a shorter wavelength than the corresponding product from wild-type GFP. In yet another class of modifications, the product derived from the modified GFP exhibits only a single excitation peak and enhanced emission relative to the product derived from wild-type GFP.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.