Extended human hematopoiesis in a heterologous host
US5625127A · kind A · utility
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8Claims
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Key dates
| Filing date | May 4, 1995 |
| Grant date | Apr 29, 1997 |
| Priority date | — |
| Expiry date | May 4, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2517/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A human hematopoietic system is provided in an immunocompromised mammalian host, where the hematopoietic system is functional for extended periods of time. Particularly, human fetal liver tissue and human fetal thymus is introduced into an appropriate site of a young immunocompromised mouse at a site supplied with a vascular system, whereby the fetal tissue results in novel formation of functional human bone marrow tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.