Method for regulating metabolism with dopamine beta hydroxylase inhibitors

US5626860A · kind A · utility

Assignees

• The Board of Supervisors of Louisiana State and Agricultural and Mechanical College · US
• Ergo Science Incorporated · US

Inventors

• Anthony H. Cincotta · Baton Rouge, US
• Albert H. Meier · Baton Rouge, US
• John M. Wilson · Helotes, US

Key dates

• Filing date: Jun 7, 1995
• Grant date: May 6, 1997
• Expiry date: Jun 7, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed herein are methods for regulating or ameliorating lipid and glucose metabolism and reducing in a vertebrate animal body fat stores, insulin resistance, hyperinsulinemia, hyperglycemia, hyperlipidemia, elevated blood lipoproteins (such as triglycerides and cholesterol including chylomicrons, VLDL and LDL) and/or increasing in the subject the plasma HDL. The methods comprise administration or timed administration of inhibitors of dopamine beta hydroxylase (DBH).