Drug-containing adhesive composite transdermal delivery device
US5626866A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 17, 1995 |
| Grant date | May 6, 1997 |
| Priority date | — |
| Expiry date | Oct 17, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/7061
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for making a transdermal drug delivery device for heat sensitive and volatile drugs is disclosed. The device contains a drug-containing adhesive composite layer having an impermeable backing material laminated to the distal surface thereof and a proximal peelable impermeable backing material adapted for removal for administering a drug to the skin or mucosa laminated to the proximal surface thereof. The method comprising the steps of providing first and second adhesive laminates each comprising a drug permeable adhesive layer having laminated to one surface one of said backing materials and having the opposing surface exposed. The drug, in gelled form and optionally containing additives such as enhancers and preservatives, is extruded onto at least one exposed surface of the first or second adhesive laminate followed by laminating together the exposed surfaces of the first and second adhesive laminate such that the adhesive layers and gelled drug are combined to form the drug-containing adhesive composite layer having the distal and proximal surfaces covered by the respective backing materials. The adhesives used in making up the laminates may be the same or different prov…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.