Disposable cartridge for an assay of a biological sample
US5627041A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Sep 2, 1994 |
| Grant date | May 6, 1997 |
| Priority date | — |
| Expiry date | Sep 2, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/25625
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A cartridge is provided to present a biological sample for analysis by an imaging instrument. The cartridge of the invention utilizes a series of channels, capillaries, reservoirs and stop junctions to precisely move a sample, reagent and diluent through the cartridge as a function of the sum of capillary, gravitational and low centrifugal forces. The operator applies a precise amount of sample to the cartridge; therefore, the cartridge fluidics need not meter the sample prior to dilution. A practical and cost effective cartridge and assay process is disclosed which overcomes many of the limitations of the prior art. Such a cartridge is especially useful with fixed volume assays which permit low centrifugal accelerations to move the fluids within the cartridge.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.