Methods and means for control of proliferation of remnant cells following surgery
US5627162A · kind A · utility
31Cited by
14References
10Claims
0Family size
Inventors
Key dates
| Filing date | Jan 18, 1995 |
| Grant date | May 6, 1997 |
| Priority date | — |
| Expiry date | Jan 18, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/728
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods to control undesired cell proliferation of remnant cells following surgery, by applying an effective amount of at least one proteoglycan-type substrate adhesion molecule (SAM) to the site of surgery. SAMs, in particular chondroitin sulfate, hyaluronic acid, and non-toxic, pharmaceutically acceptable salts thereof, alone or in a composition form, are typically used to prevent or inhibit growth of lens-related cells in a lens capsule after surgical removal of the lens, or to prevent proliferative vitreoretinopathy following retinal reattachment procedure performed with or without vitrectomy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.