Patent · US Expired

Quinoline-4-carbonylguanidine derivatives, process for producing the same and pharmaceutical preparations containing the compounds

US5627193A · kind A · utility

1Cited by
7References
27Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 31, 1996
Grant dateMay 6, 1997
Priority date
Expiry dateJan 31, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D215/52
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to quinoline-4-carbonylguanidine derivative represented by formula (1) ##STR1## and pharmaceutically acceptable salt thereof, a process for producing the same, and a Na.sup.+ /H.sup.+ exchanger inhibitor containing the compound as an active ingredient. The compounds of the present invention are useful as an agent for treating or preventing various diseases by hyperfunction of the Na.sup.+ /H.sup.+ exchanger and as a diagnostic agent for these diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.