Process for preparing sugar acetonides

US5627272A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Rainer Sobotta · Ingelheim am Rhein, DE
• Franz Klinger · Bedburg, DE
• Heinrich Schneider

Key dates

• Filing date: Sep 6, 1994
• Grant date: May 6, 1997
• Expiry date: Sep 6, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H9/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A method of preparing sugar acetonides, such as for example 1,2:5,6-Di-O-isopropylidene-.alpha.-D-glucofuranose, by reacting the corresponding sugar, e.g. D-(+)-glucose, with acetone in the presence of a Lewis acid and a carboxylic acid derivative of general formula ##STR1## wherein X is a leaving group which may be readily replaced by a hydroxyl group.