Method for analyzing oligonucleotide analogs
US5627277A · kind A · utility
1Cited by
9References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 7, 1994 |
| Grant date | May 6, 1997 |
| Priority date | — |
| Expiry date | Jan 7, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/44747
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is a substrate useful for separating unmodified and modified mononucleotides and oligonucleotides. The substrate includes at least 12% (weight:volume) polymer in at least 5M urea and at least 32% (volume:volume) organic solvent, the organic solvent being a chemically stable liquid at room temperature and having a dielectric constant of at least 20. Also provided is a method of separating unmodified and modified mononucleotides and/or oligonucleotides utilizing this substrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.