Method for galenically preparing a therapeutic composition based on aspirin
US5629022A · kind A · utility
Inventors
Key dates
| Filing date | Jun 5, 1995 |
| Grant date | May 13, 1997 |
| Priority date | — |
| Expiry date | Jun 5, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/60
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Preparation method for preparing a therapeutical composition for internal use, particularly to be administered by mouth, in galenical presentation, and containing at least one active principle in solid form adsorbed on a substrate, the active product being distributed therein as finely dispersed microparticles. The method includes dissolving the starting active principle in an appropriate solvent, impregnating the solution thus formed on a food support having an appropriate structure and pharmaceutically compatible with the active principle, and evaporating the solvent from the solution adsorbed in the support by causing the reconstitution of the active principle by formation of microcrystals adsorbed on the walls of the substrate and within the substrate. The solvent is comprised of a binary system including a main solvent of organic nature and an adjuvent of the solid type at room temperature and soluble in the main solvent. The adjuvent additionally has lubricating properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.