Patent · US Expired

Polypeptides possessing a nitrilase activity and method of converting nitriles to carboxylates by means of said polypeptides

US5629190A · kind A · utility

33Cited by
1References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 23, 1995
Grant dateMay 13, 1997
Priority date
Expiry dateMay 23, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N9/78
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention relates to novel polypeptides having a nitrilase activity and to the genetic tools for producing them, namely: PA1 the DNA sequence coding for a polypeptide having a nitrilase activity and capable of hydrolyzing nitriles to carboxylates, PA1 an analog of this sequence resulting from the degeneracy of the genetic code, PA1 a DNA sequence hybridizing with one of these sequences or a fragment thereof and coding for a polypeptide having a nitrilase activity, PA1 expression cassettes and microorganisms enabling them to be obtained. Application: enzymatic conversion of nitriles to carboxylates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.