Method of making a porous matrix particle
US5629191A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 10, 1993 |
| Grant date | May 13, 1997 |
| Priority date | — |
| Expiry date | Jun 10, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/70
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A porous particle having a generally isopycnic density with liquid growth medium, a sponge-like character and a diameter of less than 2 mm which is formed from a homogenous biologically compatible matrix is described. This particle is useful in various systems for culturing anchorage-dependent and -independent cells, and is adaptable to large scale tissue culture which permits harvesting of cell products. The method of making such a particle includes preparing a solution containing a biologically compatible material, forming droplets from the solution, freezing the droplets, drying the droplets by sublimation to form a particle, and crosslinking the biologically compatible material in the particle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.