Single chain peptide compounds having hemoregulatory activity

US5629293A · kind A · utility

Assignee

• NYCOMED IMAGING AS · NO

Inventors

• Kjell Undheim · Oslo, NO
• Peter Kremminger · Kufstein, AT
• Michael Hartmann · Pettenbach, AT

Key dates

• Filing date: Nov 30, 1994
• Grant date: May 13, 1997
• Expiry date: Nov 30, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2603/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There is disclosed single chain peptide compounds, substituted at a C.alpha.-atom of a non-terminal amino acid by a group--A which is defined in claim 1. The native .alpha.-side chain of the C.alpha. atom bonded group to group --A absent. The peptide derivatives according to the invention are useful for inhibiting cell proliferation, especially myelopoietic and bone marrow cells.