Synergistic combination of a substance with gastric acid secretion inhibiting effect and an acid degradable antibiotic
US5629305A · kind A · utility
36Cited by
2References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 16, 1995 |
| Grant date | May 13, 1997 |
| Priority date | — |
| Expiry date | May 16, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2210/0047
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A synergistic pharmaceutical combination and composition are disclosed for the treatment of gastritis and peptic ulcer containing a therapeutic amount of a proton pump inhibitor such as e.g., omeprazole or lansoprazole, which increases intragastric pH, and a therapeutic amount of an acid degradable antibacterial compound such as a penicillin or a macrolide. In particular, the combination is directed to the treatment of infections caused by Helicobacter pylori by raising the bioavailability of acid degradable antibacterial compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.