Process for producing .alpha.-hydroxyiminophenylacetonitriles
US5629442A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | May 11, 1995 |
| Grant date | May 13, 1997 |
| Priority date | — |
| Expiry date | May 11, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C255/64
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is disclosed to produce an .alpha.-hydroxyiminophenylacetonitrile of the general formula [II]: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and Z are each as defined in the specification, characterized in that a crude nitrile containing a phenylacetonitrile of the general formula [I]: ##STR2## wherein R.sup.1, R.sup.2, R.sup.3 and Z are each as defined in the specification, is reacted with an alkyl nitrite in the presence of a base, after which the reaction mixture is extracted with water and then the separated aqueous layer is neutralized with an acid. According to this production process, the desired .alpha.-hydroxyiminophenylacetonitrile can be produced with high purity, in high yield and with ease by extracting the reaction mass with water and then neutralizing the separated aqueous layer with an acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.