Two-step pretargeting methods using improved biotin-active agent conjugates
US5630996A · kind A · utility
24Cited by
8References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 16, 1993 |
| Grant date | May 20, 1997 |
| Priority date | — |
| Expiry date | Sep 16, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods, compounds, compositions and kits that relate to pretargeted delivery of diagnostic and therapeutic agents are disclosed. In particular, methods for radiometal labeling of biotin and for improved radiohalogenation of biotin, as well as related compounds, are described. Also, clearing agents, anti-ligand-targeting moiety conjugates, target cell retention enhancing moieties and additional methods are discussed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.