Lipid-polymer conjugates and liposomes
US5631018A · kind A · utility
214Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 4, 1994 |
| Grant date | May 20, 1997 |
| Priority date | — |
| Expiry date | Oct 4, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2984
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A lipid-polymer conjugate for use in forming long-circulating liposomes is disclosed. The conjugate includes a vesicle-forming lipid having covalently attached to its polar head group, one of the polymers: polyvinylpyrrolidone, polyvinylmethylether, polyhydroxypropyl methacrylate, polyhydroxypropylmethacrylamide, polyhydroxyethyl acrylate, polymethacrylamide, polydimethylacrylamide, polymethyloxazoline, polyethyloxazoline, polyhydroxyethyloxazoline, polyhydroxypropyloxazoline, or polyaspartamide. A method for preparing liposomes containing the lipid-polymer conjugate is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.