Method for making freeze dried drug dosage forms
US5631023A · kind A · utility
134Cited by
14References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 7, 1995 |
| Grant date | May 20, 1997 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses an improved technique for preparing a rapidly dispersing pharmaceutic tablet of a granular therapeutic agent which has both relatively low solubility and relatively large particle size. Xanthan gum is added to a liquid admixture of solvent, carrier components, and the granular therapeutic agent. The xanthan gum not only facilitates suspension of the granular therapeutic agent in the liquid admixture, but, more surprisingly, does so without adversely effecting the dispersion qualities and texture of the tablet in the patient's mouth upon administration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.